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2-[(2-oxo-1-naphthalenylidene)methylamino]-N-(1-phenylethyl)benzamide
CAS Number: 331830-20-7
Smiles: O=C(NCC1C=C2OCOC2=CC=1)C1C(Cl)=CC=CC=1Cl
and an increased escape latency of rats in the Morris water maze test
Alzheimer's disease and polyglutamine diseases such as Spinal and Bulbar Muscular Atrophy and Huntington’s disease
VU-0357121 - CAS# 433967-28-3 size:10mg solid 2-[(2-oxo-1-naphthalenylidene)methylamino]-N-(1-phenylethyl)benzamideVU 0357121, CAS No. 433967 28 3, is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that VU 0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site. Product information CAS Number: 433967 28 3 Molecular Weight: 305. 32 Formula: C17H17F2NO2 Synonym: VU 0357121 VU 0357121 VU0357121 Chemical Name: 4
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